Biochemistry | Ahead of Print
https://pubs.acs.org/toc/bichaw/0/0To more fully mimic ecDHFR, we also study a triple mutant of the human enzyme (F32L-PP26N-PEKN62G). Remarkably, the intrinsic KIEs, while larger in magnitude, are temperature-independent like the WT enzymes. We also construct deletion mutations of hsDHFR removing both the 62-PEKN and 26-PPLR sequences.
Biochemistry
https://pubs.acs.org/page/bichaw/about.htmlBiochemistry provides an international forum for publishing exceptional, rigorous, high-impact research across all of biological chemistry. This broad scope includes studies on the chemical, physical, mechanistic, and/or structural basis of biological or cell function, and encompasses the fields of chemical biology, synthetic biology, disease ...
Biochemistry - American Chemical Society
pubs.acs.org › journal › bichawBiochemistry recognizes and honors an individual whose scientific contributions have had a major impact on research across all of biological chemistry through the Gordon Hammes Lectureship Award. Likewise, the Scholar Award recognizes those at the bench–graduate students, postdocs, and undergraduates–for the outstanding work they do.
Biochemistry - American Chemical Society
pubs.acs.org › toc › bichawTo more fully mimic ecDHFR, we also study a triple mutant of the human enzyme (F32L-PP26N-PEKN62G). Remarkably, the intrinsic KIEs, while larger in magnitude, are temperature-independent like the WT enzymes. We also construct deletion mutations of hsDHFR removing both the 62-PEKN and 26-PPLR sequences.
Biochemistry - American Chemical Society
pubs.acs.org › page › bichawJournal Scope. Biochemistry provides an international forum for publishing exceptional, rigorous, high-impact research across all of biological chemistry. This broad scope includes studies on the chemical, physical, mechanistic, and/or structural basis of biological or cell function, and encompasses the fields of chemical biology, synthetic biology, disease biology, cell biology, nucleic acid ...
Biochemistry - American Chemical Society
https://pubs.acs.org/journal/bichawBiochemistry recognizes and honors an individual whose scientific contributions have had a major impact on research across all of biological chemistry through the Gordon Hammes Lectureship Award. Likewise, the Scholar Award recognizes those at the bench–graduate students, postdocs, and undergraduates–for the outstanding work they do.