Combating TKI resistance in CML by inhibiting the PI3K/Akt ...
link.springer.com › article › 10Jan 16, 2021 · Chronic myeloid leukemia (CML), a myeloproliferative hematopoietic cancer, is caused by a genetic translocation between chromosomes 9 and 22. This translocation produces a small Philadelphia chromosome, which contains the Bcr-Abl oncogene. The Bcr-Abl oncogene encodes the BCR-ABL protein, upregulates various signaling pathways (JAK-STAT, MAPK/ERK, and PI3K/Akt/mTOR), and out of which the ...
Soner og sonekart | Ruter
https://ruter.no/kjop-billett/sonerSoner utenfor Oslo og deler av Viken (tidligere Akershus fylke) Noen av linjene våre strekker seg utenfor Oslo og fylket som tidligere var Akershus. Sone 5V i Drammen og Lier. I sone 5V kjører vi linjene 251 og 261. Skal du reise til/fra sone 5V, anbefaler vi deg å kjøpe billett fra Brakar i BrakarBillett-appen.
AKT - Bradford VTS
www.bradfordvts.co.uk › mrcgp › aktThe AKT Content Guide & Curriculum Self-Assessment. The first thing to look at is the AKT Content Guide which is downloadable from the resources link above . The RCGP’s AKT Core Group has developed this learning resource to complement the curriculum which essentially lists the topics that could be tested in the AKT.