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gingraslab.orgSignalling. Some of our core research interests have been the study of signaling pathways that are deregulated in cancers and rare diseases. These include mTORC1 activation, receptor tyrosine kinase signalling, the STRIPAK phosphatase and kinase complex (implicated in CCM disease) and the Hippo pathway, between the last two of which we interestingly discovered novel and important connections.
Cavernous hemangioma - Wikipedia
https://en.wikipedia.org/wiki/Cavernous_hemangiomaCavernous hemangioma, also called cavernous angioma, venous malformation, cavernoma, or cerebral cavernous malformation (CCM) (when referring to presence in the brain) is a type of venous malformation due to endothelial dysmorphogenesis from a lesion which is present at birth. Despite its designation of a hemangioma, it is not a tumor as it does not display …