Feb 28, 2021 · Dear Colleagues, Mast cells (MC) are multifunctional cells regulating innate and adaptative immune system. MC participate in detection of harmful pathogens like viruses, bacteria, parasites and toxins, play the role in wound healing, cancer and tumor progression.
Introduction. Psoriasis is a chronic inflammatory disease that commonly manifests as erythematous plaques with adherent silvery scales 1.The causes of psoriasis are complex, and they include psoriasis autoantigens, the innate and adaptive immune systems, psoriasis-associated susceptibility genes, and environmental factors 1, 2.
31.08.2021 · Special Issue "Psoriasis (PsO) and Psoriatic Arthritis (PsA)" A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section " Molecular Immunology ". Deadline for manuscript submissions: closed (31 August 2021) .
23.08.2021 · Cardiovascular risk factors are one of the most common comorbidities in psoriasis. A higher prevalence of hypertension, insulin resistance and type 2 diabetes, dyslipidemia, obesity, metabolic syndrome, depression, as well as cardiovascular disease was confirmed in psoriatic patients in comparison to the general population. Data suggest that psoriasis and systemic …
Tytuł angielski: Treatment of moderate to severe plaque psoriasis with ... .nlm.nih.gov/pmc/articles/PMC5751117/pdf/ijms-18-02514.pdf [dostęp: 26.01.2018]
Psoriasis is a common, chronic, inflammatory, immune-mediated skin disease affecting about 2% of the world's population. It is associated with many comorbidities including arthritis, metabolic syndrome and an increased cardiovascular disease risk, increasing the risk of mortality due to myocardial infarction and stroke.
Special Issue "New Insights into Psoriasis". A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section " Molecular Pathology, Diagnostics, and Therapeutics ". Deadline for manuscript submissions: 31 May 2022 .
30.09.2017 · Therapeutic interventions in psoriasis need to take into account this new information. In addition, new pharmacogenomics data are important for planning more individualized treatment strategies. This Special Issue of IJMS provides a comprehensive synopsis of the state-of-the-art in psoriasis, its pathogenesis and its management.
28.02.2021 · Dr. Bogusław Nedoszytko Prof. Dr. Peter Valent Prof. Dr. Marek Niedoszytko Guest Editors. Manuscript Submission Information. Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline.
08.01.2022 · Psoriasis is a chronic inflammatory skin disease with systemic manifestation, in which psychological factors play an important role. The etiology of psoriasis is complex and multifactorial, including genetic background and environmental factors such as emotional or physical stress. Psychological stress may also play a role in exacerbation of psoriasis, by …
Int J Med Sci 2021; 18(16):3794-3799. doi:10.7150/ijms.61973 This issue ... Psoriasis is a chronic inflammatory disease that involves both the innate and ...
Apr 22, 2014 · Th1 CXCR3+ CCR5+ lymphocytes chemotaxis, reported in psoriasis, is also mediated by the increased expression of chemokines such as CXCL10 and CCL5 in the psoriatic skin . Interleukin-8, i.e. CXCL8 chemokine (inflammation mediator synthesized de novo by mast cells) is the best described chemokine/cytokine in the context of psoriasis. It is a ...
29.11.2021 · Interleukin 33 (IL-33) belongs to the IL-1 family and is produced constitutively by epithelial and endothelial cells of various organs, such as the skin. It takes part in the maintenance of tissue homeostasis, repair, and immune response, including activation of Th2 lymphocytes. Its involvement in pathogenesis of several inflammatory diseases including …
ijms-logo ... Dr. Bogusław Nedoszytko ... Interests: molecular basis of mastocytosis; psoriasis; atopic dermatitis; epigenetic changes in psoriasis and ...
Methods We analysed 166 patients with psoriasis vulgaris (134 with type I and 32 with type II) and 65 healthy controls. The polymorphisms –238G/A and –308G/A in the promoter region of the TNF‐α gene were typed using the amplification refractory mutation system–polymerase chain reaction method.
Mastocytosis is a rare and complex disease characterized by expansion of clonal mast cells (MC) in skin and/or various internal organ systems. Involvement of internal organs leads to the diagnosis of systemic mastocytosis (SM).