Biomolecules | Free Full-Text | In-Depth Molecular Dynamics ...
www.mdpi.com › 2218-273X › 12/1/77Jan 05, 2022 · GAGs exhibit a high level of conformational and configurational diversity, which remains untapped in terms of the recognition and modulation of proteins. Although GAGs are suggested to bind to more than 800 biologically important proteins, very few therapeutics have been designed or discovered so far. A key challenge is the inability to identify, understand and predict distinct topologies ...