Repositioning Food and Drug Administration-Approved Drugs for ...
pubs.acs.org › doi › 10Dec 27, 2021 · Biliverdin IXβ reductase B (BLVRB) has recently been proposed as a novel therapeutic target for thrombocytopenia through its reactive oxygen species (ROS)-associated mechanism. Thus, we aim at repurposing drugs as new inhibitors of BLVRB. Based on IC50 (<5 μM), we have identified 20 compounds out of 1496 compounds from the Food and Drug Administration (FDA)-approved library and have clearly ...
What is medicinal chemistry? – Demystifying a rapidly ...
www.ncbi.nlm.nih.gov › pmc › articlesSep 01, 2017 · Medicinal chemistry is also an art where the artist uses a subtle mixture of knowledge, experimental learning, creativity, intuition, boldness, and serendipity to paint the right canvas (Jung and Radi). Medicinal chemistry is an adventure, a treasure hunt that seeks to offer us higher life quality. The treasure often lies outside the box. Medicinal chemistry is hope for people fighting against diseases (Arai) with medicinal chemists being the front-line solders with an up-lifting attitude.
CAS Source Index (CASSI) Search Tool
cassi.cas.org › resultsIndian Journal of Chemistry Abbreviation: Indian J. Chem. CODEN ISSN: IJOCAP 0019-5103: Publication Title: Korean Journal of Medicinal Chemistry: Abbreviation: Korean J. Med. Chem. CODEN ISSN: KJMCE7 1225-0058: Publication Title: Journal of Medicinal Chemistry: Abbreviation: J. Med. Chem. CODEN ISSN: JMCMAR 0022-2623: Publication Title: Open Journal of Medicinal Chemistry: Abbreviation
Journal of Medicinal Chemistry: List of issues
https://pubs.acs.org/loi/jmcmarJournal of Medicinal Chemistry (1963 - onwards) Journal of Medicinal and Pharmaceutical Chemistry (1959 - 1962) CURRENT ISSUE; VIEW ALL ISSUES; Get e-Alerts. CURRENT ISSUE; VIEW ALL ISSUES; 2020s; 2010s; 2000s; 1990s; 1980s; 1970s; 1960s; 1950s; 2021; 2020; Archive of 2021 Online Issues. December 23, 2021 Vol. 64 Issue 24.
Journal of Medicinal Chemistry | Vol 64, No 24
pubs.acs.org › toc › jmcmarJournal of Medicinal Chemistry 2021, 64, 21, 15787-15798 (Article) Publication Date (Web): October 27, 2021. Abstract. Full text. PDF. ABSTRACT. Inhibition of TGFβ signaling in concert with a checkpoint blockade has been shown to provide improved and durable antitumor immune response in mouse models.
Call for Papers: 6-Journal Virtual Special Issue on ...
axial.acs.org › 2021/07/13 › call-for-papers-6Jul 13, 2021 · Journal of Medicinal Chemistry. Submission Deadlines: July 31, 2021, for Perspectives; October 31, 2021, for Articles and Drug Annotations. The Journal of Medicinal Chemistry invites submissions across the full spectrum of epigenetics, including epigenetic studies focused on human and non-human species. The Journal of Medicinal Chemistry is traditionally associated with full-length papers that report substantial studies in medicinal chemistry, and we are keen to receive such submissions.