Methadone - Wikipedia
https://en.wikipedia.org/wiki/MethadoneMethadone acts by binding to the µ-opioid receptor, but also has some affinity for the NMDA receptor, an ionotropic glutamate receptor. Methadone is metabolized by CYP3A4, CYP2B6, CYP2D6, and is a substrate, or in this case target, for the P-glycoprotein efflux protein, a protein which helps pump foreign substances out of cells, in the intestines and brain. The bioavailability and elimination half-life of methadone are subject to substantial interindividual variability. Its main route of admin…
Methadone - Wikipedia
en.wikipedia.org › wiki › MethadoneMethadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for opioid maintenance therapy in opioid dependence and for chronic pain management. It is most commonly used to treat addiction to heroin or other opioids, and to reduce risk of fatal overdose from street drugs.
Melnea Cass Boulevard - Wikipedia
https://en.wikipedia.org/wiki/Melnea_Cass_BoulevardMelnea Cass Boulevard is a street in Boston, Massachusetts, running perpendicular to the line between Nubian Square in Roxbury and the South End.It is named after local community and civil rights activist Melnea Cass.The road's right-of-way was originally planned to be part of Interstate 695, until its cancellation. There is also an MBTA Silver Line station named Melnea Cass …
Mass and Cass - Wikipedia
en.wikipedia.org › wiki › Mass_and_CassMass and Cass, also known as Methadone Mile or Recovery Road, is a tent city located at and around the intersection of Melnea Cass Boulevard and Massachusetts Avenue in Boston, Massachusetts. It has been characterized as "the epicenter of the region's opioid addiction crisis." Drug and homelessness issues