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ISO 15819:2014(en), Cosmetics — Analytical methods ...
https://www.iso.org › obp
Among N-nitrosamines, N-nitrosodiethanolamine (NDELA) has been recognized as a potential contaminant of cosmetics. ... This latter method uses advanced technology ...
Risk assessment of N-nitrosodiethylamine (NDEA) and N ...
pubmed.ncbi.nlm.nih.gov › 29694274
N-nitrosamines and their precursors found in cosmetics may be carcinogenic in humans. Thus the aim of this study was to carry out risk assessment for N-nitrosamines (N-nitrosodiethanolamine [NDELA], N-nitrosodiethylamine [NDEA]) and amines (triethanolamine [TEA], diethanolamine [DEA]) levels in cosm …
N-Nitrosodiethanolamine Bis(2-hydroxyethyl)nitrosamine 1116-54-7
www.sigmaaldrich.com › US › en
N-Nitrosodiethanolamine (NDELA), an environmentally prevalent, potent carcinogen, undergoes competitive rat liver microsome-mediated oxidation at both the alpha (adjacent to N)- and beta-positions of the 2-hydroxyethyl chains. The former process, alpha-hydroxylation, is detected by the formation of glycolaldehyde (determined as its
NDELA | C4H10N2O3 | ChemSpider
http://www.chemspider.com › Che...
NDELA. Molecular FormulaC4H10N2O3; Average mass134.134 Da; Monoisotopic mass134.069138 Da; ChemSpider ID13587. More details: Systematic name.
Opinion on NDELA in Cosmetic Products and Nitrosamines in ...
https://ec.europa.eu/health/scientific_committees/consumer_safety/d…
NDELA in Cosmetic Products and Nitrosamines in Balloons 6 1.1 In 19936 the USEPA derived an oral slope factor of 2.8 per 1 mg NDELA/kg body weight/day. This resulted in a VSD of 0.36 ng/kg bw/day. Some experts considered this VSD for NDELA inappropriate since it is lower than the VSD for N-nitrosodimethylamine (NDMA) which is known to be a stronger
Cosmetics NDELA Test - SGS TIC Mall
https://ticmall.sgs.com › product
With the specialized chemical laboratories in SGS, we can help you examine the N-nitrosodiethanol-amine (NDELA) content of your cosmetic products to ensure ...
Forsiden - NDLA
https://ndla.no
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Determination of N-nitrosodiethanolamine, NDELA in cosmetic ...
www.sciencedirect.com › science › article
May 15, 2015 · Both NDELA and NDELA-d8 were well-retained and separated on the PGC column. Chromatographic separation for the adequate retention of NDELA and IS was achieved within 7 min. The retention time of the NDELA was 2.1 min. Representative chromatograms for blank sample, standard spiked in TEA and foam cleanser are shown in Fig. 7.
(NDELA) - osha.gov
https://www.osha.gov/sites/default/files/methods/osha31.pdf
NDELA has been found in air samples taken inside workplaces where materials known to contain NDELA and its precursors are in use (Section 4.11). In fiscal year 1980, the Carcinogen/Pesticide Branch of the OSHA Analytical Laboratory completed more than 400 determinations for NDELA. This was the ninth most requested compound for analysis by that ...
Opinion on NDELA in Cosmetic Products and Nitrosamines in ...
ec.europa.eu › health › scientific_committees
NDELA in Cosmetic Products and Nitrosamines in Balloons 6 1.1 In 19936 the USEPA derived an oral slope factor of 2.8 per 1 mg NDELA/kg body weight/day. This resulted in a VSD of 0.36 ng/kg bw/day. Some experts considered this VSD for NDELA inappropriate since it is lower than the VSD for N-nitrosodimethylamine (NDMA) which is known to be a stronger
N-Nitrosodiethanolamine | C4H10N2O3 - PubChem
https://pubchem.ncbi.nlm.nih.gov › ...
N-Nitrosodiethanolamine (NDELA) was administered to rats whose bile was drained into the duodenum of a second group of animals, in which the natural bile ...
NDELA - What does NDELA stand for? The Free Dictionary
https://acronyms.thefreedictionary.com › ...
NDELA. Acronym, Definition. NDELA, N-nitrosodiethanolamine. Copyright 1988-2018 AcronymFinder.com, ...
(NDELA)
www.osha.gov › sites › default
NDELA has been found in air samples taken inside workplaces where materials known to contain NDELA and its precursors are in use (Section 4.11). In fiscal year 1980, the Carcinogen/Pesticide Branch of the OSHA Analytical Laboratory completed more than 400 determinations for NDELA. This was the ninth most requested compound for analysis by that ...
Occurrence of N-nitrosodiethanolamine (NDELA) in cosmetics ...
https://pubmed.ncbi.nlm.nih.gov/18498455
The average recovery for NDELA is 99%, range 86-112% (n = 4) and the limit of quantification is 5.3 mug kg (-1). The GC-TEA method was used to determine the NDELA content of 48 cosmetics including gels, shampoos, cremes, milks, conditioners and foams. All determinations were done in duplicate, and for every 10 cosmetics a recovery experiment ...
N-NITROSODIETHANOLAMINE (NDELA) Method no.: 31 Matrix
http://www.osha.gov › files › methods › osha31
Bulk samples are screened for NDELA by high performance liquid chromatography (HPLC) with ultraviolet (UV) detection. Bulk samples which give positive HPLC/UV ...
Formation and destruction of NDELA in MEA and DEA - SINTEF
https://www.sintef.no/globalassets/project/hipercap/pdf/formation_an…
Decomposition of NDELA and NDMA in fresh 30wt% MEA • Start concentration • NDMA 7620 ng/ml • NDELA 624 ng/ml • LOQ • NDMA 250 ng/ml • NDELA 50 ng/ml • Concentration of NDMA and NDELA are below the LOQ after 2.5 hours
N-Nitrosodiethanolamine | C4H10N2O3 - PubChem
pubchem.ncbi.nlm.nih.gov › compound › n-nitrosodi
N-Nitrosodiethanolamine | C4H10N2O3 | CID 14223 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ...
Opinion on NDELA in cosmetic products and nitrosamines in ...
https://op.europa.eu › publication
Some of these nitrosamines, such as N-nitrosodiethanolamine (NDELA) and N-nitrosodimethylamine (NDMA) are classified as category 1B ...
Ndela | Sigma-Aldrich
https://www.sigmaaldrich.com › se...
N-Nitrosodiethanolamine. Synonym(s): NDELA, 2,2′-(Nitrosoimino)bisethanol, N,N-Diethanolnitrosamine, Bis ...