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How does indirect action affect DNA? ... Ionizing radiation can also affect important molecules other than DNA. For example, it can break the ...

In this survey, emphasis was placed on the main photoreactions of nucleic acid components, involving both direct and indirect effects. The main UVB- and UVA-induced DNA photoproducts, together with the mechanisms of their formation, are described.

Direct-type damage results from radiation energy being deposited directly into the DNA, whereas indirect damage occurs when the species ...

Direct-type damage results from radiation energy being deposited directly into the DNA, whereas indirect damage occurs when the species created by the ...

They may interact directly with biological molecules, including DNA, or they may react to produce additional chemical oxidizing species. An example of a common free radical that one would expect from irradiation of water in the body would be the hydroxy free radical, symbolized OH, a very reactive species that could directly result in a bond rupture in a DNA strand.

Oct 01, 2001 · DOI: 10.1016/S1011-1344(01)00206-8 Corpus ID: 11538306. Direct and indirect effects of UV radiation on DNA and its components. @article{Ravanat2001DirectAI, title={Direct and indirect effects of UV radiation on DNA and its components.}, author={Jean‐Luc Ravanat and Thierry Douki and Jean Cadet}, journal={Journal of photochemistry and photobiology.

Indirect Effect. Radiolytic Decomposition of Water in a Cell. If a cell is exposed to radiation, the probability of the radiation interacting with the DNA ...

Indirect action is predominant with low LET radiation, e.g. X and gamma rays. Module Medical VIII. - 16. Biochemical reactions with ionizing radiation. DNA ...

Direct and indirect lesions on DNA strands are likely to induce mutations, the former of which is caused by ions hitting on DNA molecules, while ...

Feb 19, 2013 · We report the effect of the DNA hydration level on damage yields induced by soft X-rays and photoemitted low-energy electrons (LEEs) in thin films of plasmid DNA irradiated in N2 at atmospheric pressure under different humidity levels. Contrary to a dilute solution of DNA, the number of H2O molecules per nucleotide (Γ) in these films can be varied from Γ = 2.5 to ∼33, where Γ ≤ 20 ...

How does indirect action affect DNA? Ionizing radiation can also affect important molecules other than DNA. For example, it can break the bonds holding water molecules together. This creates hydrogen (H +) and hydroxyls (OH -) ions. These are called free radicals .

Dec 14, 2019 · The probability of the radiation interacting with the DNA molecule is very small since these critical components make up such a small part of the cell. Indirect effects. Indirect effects are caused by interaction of radiation usually with water molecules. Each cell, just as is the case for the human body, is mostly water.

The probability of the radiation interacting with the DNA molecule is very small since these critical components make up such a small part of the cell. Indirect effects. Indirect effects are caused by interaction of radiation usually with water molecules. Each cell, just as is the case for the human body, is mostly water.

... LEEs can indirectly damage DNA. ... been made on the indirect effect ...

14.12.2019 · The probability of the radiation interacting with the DNA molecule is very small since these critical components make up such a small part of the cell. Indirect effects. Indirect effects are caused by interaction of radiation usually with water molecules. Each cell, just as is the case for the human body, is mostly water.

Radiation damage to the cell can be caused by the direct or indirect action of radiation on the DNA molecules.

Direct and indirect effects of UV radiation on DNA and its components In this survey, emphasis was placed on the main photoreactions of nucleic acid components, involving both direct and indirect effects. The main UVB- and UVA-induced DNA photoproducts, together with the mechanisms of their formation, are described.